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The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids

Vitamin injections are generally considered safe and well-tolerated

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[1] Plain sterile water has no preservative and should be used right away

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Typically, the initial treatment for B12 deficiency involves a higher dose, followed by regular maintenance injections