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The chief characteristic of UC, a chronic inflammatory colon disease, is continued mucosal surface inflammation extending from the rectum to the proximal colon region (Binabaj et al

Reserve it for acute episodes rather than daily prevention

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TJ complexes are primarily composed of transmembrane proteins including occludins, junctional adhesion molecules, and claudin family members that function collectively to form pores with selective permeability to ions and molecules (Brenchley and Douek 2012

Intracellular ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG) ranges from 10 to 100

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