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In the later stages of stroke, microglial cells contribute to the remodeling of the ECM by secreting MMPs such as MMP-3, MMP-9, and MMP-19 [135]

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It had also been discounted for the treatment of obesity because there was some prec-clinical evidence to suggest it was linked with weight gain

Preclinical studies have shown that long-term infusion of BDNF into the midbrain of rats increases levels of BDNF in several regions, including the neocortex

The dTAG system for immediate and target-specific protein degradation

In addition, nasal administration of exendin-4 contributed to the decrease in A accumulation (Kamei et al., 2018)