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Therefore, as opposed to Prx3, Prx5 has been viewed mainly as a cytoprotective antioxidant enzyme rather than as a redox sensor and appears to be a unique Prx exhibiting specific functional and structural feature (Knoops et al., 2011

Asbaghi O, Ghanbari N, Shekari M, Reiner , Amirani E, Hallajzadeh J, Mirsafaei L, Asemi Z

doi: 10.1111/jth.15130 54 DatzmannTTrgerK

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The sequential introduction advantage Starting tirzepatide first and tolerating it well before introducing berberine staggers the GI adaptation periods