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Clinically studied to influence thousands of genes, this molecule promotes regeneration, repair, and protective pathways across multiple tissues including skin, connective tissue, hair follicles, lungs, bones, and the nervous system

2015;10:e0137384

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In vitro studies have demonstrated that overexpression of Angiogenin, a RNase associated with familial ALS, activates NRF2 which protects astrocytes from oxidative stress ( Collectively, these data show that the NRF2 pathway is dysfunctional in various neurodegenerative diseases and the effects of the reduced or lost activity of the NRF2-mediated antioxidant pathway in the brain are summarized in Figure 3

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