This provides erythrocytes with a rapid, but inefficient source of ATP because anaerobic glycolysis releases only approximately 7% of the energy generated when glucose is completely oxidised to water and carbon dioxide
The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
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GLP-1, or glucagon-like peptide-1, is a naturally occurring hormone that helps regulate blood sugar and appetite
Biochem Biophys Res Commun (2009) 380:449
