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This was due to the increased CYP3A4 enzymes which cause the chemo-drugs to be removed too quickly 23

It can also be used for irregular menstrual cycles, to improve pregnancy rates [161]

Despite the burgeoning literature on the safety and efficacy of GLP-1 RAs, existing systematic reviews and meta-analyses predominantly focus on populations with T2DM, where gastrointestinal symptoms may be confounded by the underlying disease pathology [7]

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