Comparative metabolic effects of semaglutide, tirzepatide, and retatrutide in a monogenic (db/db) mouse model of obesity
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That gets reviewed by a clinician, who checks BMI thresholds and screens for contraindications including pregnancy, acute pancreatitis, and medullary thyroid cancer
However, the application of these interventions poses a risk of dysbiosis, where medication-induced changes may lead to an imbalance in microbial populations, exacerbating symptoms rather than alleviating them [178,179,180]
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