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This is accompanied by a shift in macrophage populations, with a higher number of pro-inflammatory M1 macrophages and reduced anti-inflammatory M2 macrophages in Hunner lesions

For PET, the most plausible dominant sources are the breakdown of high-volume packaging (food/beverage containers, especially bottles) and the widespread use of PET/polyester fibres in textile applications (e.g., clothing, carpets), resulting in a substantial upstream pool of PET waste in the environment that can subsequently fragment into smaller particles under environmental stressors [5]

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HORIUCHI, N., ANDO, S., & SUZUKI, A

10 Mechanistic model of KL1 -mediated sensitization of intracellular S