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Archived from the original on 30 November 2021

Runners knee is most common in middle aged women and people who are overweight

In a 72-week trial in adults with obesity without diabetes, the mean percentage change in weight was -15.0% (5 mg), -19.5% (10 mg), and -20.9% (15 mg) vs -3.1% with placebo

Importantly, most gastrointestinal events were mild-to-moderate in severity, and 92.8% of participants completed the full two-year trial, indicating that long-term tolerability was generally good

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