However, under some conditions in which NAPQI is not effectively detoxified, usually in the case of paracetamol overdose, it causes severe damage to the liver
References: Vitamin B 12 CPhA Monograph
Alternatively, events occurring within the GB itself may provide another possible mechanism for the increased risk of metabolic derangements following cholecystectomy
The American Thyroid Association recommends checking thyroid-stimulating hormone (TSH) levels 4-6 weeks after initiating levothyroxine or changing doses, then every 6-12 months once stable
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