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There was no significant difference in mean GH peaks between leptin-deficient and leptin-replete controls, suggesting that leptin does not play a significant role in the GH suppression seen in obese humans, and that the decreased GH secretion of obesity is mediated via other mechanisms (383)

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For additional context on this category, readers may reference related analysis on best peptides for boosting growth hormone published previously

Peptide safety and risks covers these considerations comprehensively

Increased lean body mass: Some studies indicate it can increase lean body mass, but not necessarily strength or physical function