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Endosomal maturation is a complex process that intertwines anterograde trafficking from trans -Golgi network (TGN) derived vesicles with endocytosed material from the cells exterior, ultimately to be degraded, recycled and/or sent to different organelles ( ELO2 (formerly FEN1) and ELO3 (formerly SUR4) simultaneously (Revardel et al., 1995)

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Sulforaphane-loaded ultradeformable vesicles as a potential natural nanomedicine for the treatment of skin cancer diseases