At the University of California, San Francisco School of Pharmacy, researchers in the Department of Pharmaceutical Chemistry are tackling that challenge from multiple directions, studying how toxic proteins accumulate in the brain, developing tools to detect disease earlier, and exploring new therapeutic approaches that target the biological processes driving neurodegeneration
Background Alzheimers disease (AD) is a neurodegenerative disease characterized by progressive decline in cognitive function, affecting millions of people worldwide
GLP-1 medications like Ozempic, Wegovy and Zepbound are well-known for their powerful weight-loss benefits
Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Philipps G, Thomashow LS
Strengthening the strength of contractions in the stomach Improving the regularity of contractions in the jejunum Speeding up how quickly the stomach empties, into the small intestine
Thus, we hypothesize that Wisp1 may dually impact adipose tissue and pancreatic -cell adaptation in an obesogenic context, having a role in obesity-induced alterations in whole body glucose homeostasis