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Therefore, only in rare occasions a substance is included in S0 after a case-by-case evaluation

10.1016/j.colsurfb.2019.05.025 [DOI] [PubMed] [Google Scholar] Hou J., Deng M., Li X., Liu W., Chu X., Wang J., et al

When to seek help red flags: Contact your GP or trial clinician promptly if you experience persistent or worsening nausea and vomiting, are unable to keep fluids down for more than 24 hours, or notice significant unintentional weight loss or difficulty maintaining adequate nutrition

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Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice