Unfortunately, we were unable to harvest sufficient A2780DPP/GSTP1 knockdown cells to perform western blotting, cytotoxicity assays or more detailed phenotypic characterisation, but our confirmation of GSTP1 knockdown, together with selective platinum toxicity in puromycin-resistant clones is consistent with an essential role for GSTP1 in glutathione conjugation and cisplatin detoxification
Provides brain and gut-brain axis support
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