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Mechanisms of action: Vitamin B6 is a cofactor for over 140 enzymatic functions and enzymes involved in synthesizing several neurotransmitters, including serotonin, dopamine, and GABA

Common side effects include nausea, vomiting, and diarrhea, most prominent during dose titration

After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached

This frequency makes them a practical and effective solution for maintaining optimal B12 levels

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