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The cutting-edge RNAseq approach of this study also provided an exciting opportunity for investigating the integrated cross-kingdom interactions of multibiome such as viruses (other than SARS-CoV-2) and archaea which contributed about 20.0% of the total microbial sequence reads

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Collectively, these data raise the possibility that the GSK3-CaMKK2-CaMK4 signalling axis is a principal site of action through which lithium increases BDNF expression and exerts its anti-manic effects