The combination group included those who added a newer generation GLP-1RA (i.e., exenatide once weekly [OW], dulaglutide, semaglutide OW T2D, or oral semaglutide) or dual GLP-1/GIP agonist (tirzepatide T2D) to their SGLT2i (i.e., canagliflozin, dapagliflozin, empagliflozin, ertugliflozin, or bexagliflozin) treatment, with persistent use of a GLP-1RA and SGLT2i for 180 days each and an overlap 120 days, where the gap after exhaustion of days supply was required to be 30 days
Along the lines of adaptation, lets not overlook an essential yet often concerning side effect: fatigue
For any facility producing injectable drug products, the cleanroom environment is the last line of defense against contamination
The Glp-1 receptor agonists exendin-4 and liraglutide alleviate oxidative stress and cognitive and micturition deficits induced by middle cerebral artery occlusion in diabetic mice
Junjie Guo: Writing - review & editing
Walking, particularly at a comfortable pace, promotes disc nutrition through the pumping action that drives fluid exchange
