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The collaborative effort between Birsoys metabolic regulation group and Richard Hites structural biology lab was instrumental in resolving the biochemical features of the SLC33A1 transporter

RAGE (by 16.6%, 48.4%, 52.2%, 64.9% and 77.9%, respectively) (Fig

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This dose is similar to that used in other studies examining central cardiovascular effects of Ex-4 in rodents and is well below the effective peripheral dose

A high-throughput screen for compounds that would alter hypoxia-induced SG dynamics in GBM cells previously identified the selective estrogen receptor modulator (SERM) raloxifene as preventing SG dissolution following hypoxic stress release, resulting in cell death [18]