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"I don't know how they're going to put the genie back in the bottle," Lee told AFP

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This suggestion was wrong since drugs that increase ACE2 expressions, like ibuprofen and angiotensin receptor blockers (ARBs), are protective rather than harmful when used in Covid-19 (Kelleni 2020

However, glucagon also: Increases energy expenditure: Glucagon promotes thermogenesis and fat oxidation Targets the liver directly: The liver has no GLP-1 or GIP receptors but is rich in glucagon receptors Reduces liver fat: Glucagon receptor activation may ease oxidative stress in liver mitochondria Provides anti-fibrotic benefits: Improved fat oxidation can improve mitochondrial function When combined with GLP-1 and GIP agonism, the glucagon components blood sugar effects appear to be counterbalanced while its metabolic benefits are retained