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Reduced physical activity and higher carbohydrate intake may contribute to increased body fat, but they do not fully account for the up to 50% decrease in lean body mass observed between ages 20 and 80

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These investigations focus on peptide selectivity and molecular signaling mechanisms within controlled preclinical research environments

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showed ERR and PGC-1 function as effectors in IFN--induced host defense by enhancing macrophage ROS production [49]a process potentially linked to ferroptosis susceptibility