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This is a particular issue for drug metabolizing enzymes, especially cytochrome P450, which are substantially downregulated [139]

Always keep it protected from light to maximize its lifespan

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Furthermore, certain medications, like proton pump inhibitors for acid reflux, metformin for diabetes, and some medications for peptic ulcers or heartburn, can impair your bodys ability to process Vitamin B12

Because it's a salt and is often of lower molecular weight, it tends to have better penetration in topical skin care