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doi: 10.1161/CIRCULATIONAHA.125.074545 Summary Keywords cardiovascular outcomes, SGLT2 inhibitors, GLP-1 agonists, combination therapy, heart failure, renal outcomes Citation Aristizbal-Colorado D, Corredor-Rengifo D, Sierra-Castillo S, Lpez-Corredor C, Vernaza-Trujillo D-A, Weir-Restrepo D, Izquierdo-Condoy JS, Ortiz-Prado E, Rico-Fontalvo J, Gmez-Mesa J-E, Abreu-Lomba A and Rivera-Martnez W-A (2025) A decade of progress in type 2 diabetes and cardiovascular disease: advances in SGLT2 inhibitors and GLP-1 receptor agonists a comprehensive review
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GLP-1 is a substrate with a high affinity for DPP-4 (direct target)
These on-switches are completely separate from the ones that semorelin activates, enabling them to work synergistically to accomplish the same task, and do so with no effect on the rest of your bodys hormones
Tracking the PA number and the submission date matters for follow-up
Am J Med 2015;128:1281e7
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