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By activating both GLP-1 and GIP receptors, Tirzepatide closely mimics the bodys natural incretin hormones that help regulate appetite, glucose metabolism, and weight control, leading to significantly greater weight reduction compared to treatments based solely on GLP-1 receptor agonists

Consider periodic attempts to step down to H2 blockers or lifestyle management alone

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Endocrinology 145 , 36523657 (2004)

Reference: Cheng CY, Lo SC, Huang CN, Yang YS, Wang YH, Kornelius E

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