Yes, CagriSema is a fixed-dose combination of semaglutide 2.4 mg and cagrilintide 2.4 mg administered as a single once-weekly injection
Kraus et al., Nature (2014), on NNMT and diet-induced obesity
The multiple sclerosis model using cuprizone-induced demyelination demonstrated reduced motor disability and preserved myelin with peptide treatment
all mechanistic and efficacy evidence is animal-derived or anecdotal, placing overall confidence at Low to Very Low for systemic human claims
, 48 , 303-307, doi: Dequanter, D., Van De Velde, M., Bar, I., Nuyens, V., Rousseau, A., Nagy, N., Vanhamme, L., Vanhaeverbeek, M., Brohe, D., Delre, P., Boudjeltia, K., Lothaire, P., and Uzureau, P
These actions have been studied in BBB models