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They identified a strong response endotype, which consisted of a subgroup of patients who saw significantly better outcomes than other participants

Clinicians began exploring this approach for a few reasons: Not everyone needs aggressive appetite suppression to improve metabolic health Some people are more sensitive to GLP-1 medications Side effects often increase with higher doses Cost and long-term sustainability matter Women, in particular, started asking different questions

A.SavilleJ.et al (2022)

Once-Weekly Semaglutide in Adults With Alcohol Use Disorder National Institute on Alcohol Abuse and Alcoholism

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[35] Tangvarasittichai S