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J Inorg Biochem 103:657665

Experimental design considerations include the importance of timing senolytic administration relative to senescence induction or disease progression, as the biological context affects both efficacy and interpretation of results

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The same group of patients exhibited elevated ALT but reduced APAP glucuronide levels, suggesting that UGT1A6*2 polymorphism is a modifier of acetaminophen glucuronidation in patients with abnormal liver function