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This approval is a big step for helping those with higher weight reach their weight management goals after trying other medications or lifestyle changes with no success

Semaglutide has moderate interactions with at least 23 other drugs

Further studies, including final evaluations from regulatory bodies, are called for to discard a causal link between GLP-1RA and suicidality

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Pharmacy availability at approval influences which formulations can be prepared and dispensed at that time

doi: 10.1056/NEJMoa2024816 96 The EMPA-KIDNEY Collaborative GroupHerringtonWGStaplinNWannerCGreenJBHauskeSJet al