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Notably, metformin has been shown to ameliorate oxidative stress as an antioxidant in individuals with type 2 diabetes 16,17,18

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Particularly, preventive effects on various inflammatory and infectious diseases are discussed, as numerous VKPDs presumably have immune system-associated functions, which is, for example, illustrated by high dp-ucMGP plasma levels, which are related to reduced respiratory capacity with an unfavorable effect on asthma but also COVID-19

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