How Individual Metabolism Affects GLP-1 Duration Your body's ability to process GLP-1 medications depends on several factors, including kidney and liver function, body composition, age, and genetic variations in peptide sensitivity
10.1172/JCI129317 J Clin Invest
In particular, long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) can cause gastric mucosal damage as they can inhibit mitochondrially encoded cytochrome C oxidase I (MT-CO1, also known as COX-1) and block its protective effect on gastric mucosa
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