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These findings should be examined in independent cohorts before these results are applied in a clinical setting

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The adenylated form of ThTP (AThTP) is found in mammalian tissues, but the enzyme(s) of its synthesis lose their activity during purification, and this interferes with their identification (140)

Neuroscience 149:91730, PMID: 17936517 Hargreaves IP, Sheena Y, Land JM, Heales SJ (2005) Glutathione deficiency in patients with mitochondrial disease: implications for pathogenesis and treatment