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The optimal ratios between components for different applications have not been scientifically established through controlled studies

While semaglutide targets the GLP-1 receptor alone, tirzepatide activates both GLP-1 and GIP receptors simultaneously, a dual mechanism that clinical trials suggest may drive greater weight reduction for certain individuals

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Novo Nordisk is positioning its new obesity drug, CagriSema, to potentially lead to at least 25% weight loss in patients, setting a new benchmark in the competitive weight-loss drug market