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It is used by every cell in the body to detoxify metabolic, drug, and environmental toxins

72 Ionizing radiation (IR), particularly at high doses (5 Gy), leads to irreversible DNA damage, triggering MSCs to form ectopically pigmented melanocytes (EPMs), which are associated with PHG

Natl Sci Rev

10.1016/j.ymeth.2016.09.013 22

Otherwise said, entry into the replication phase is blocked by the action of melatonin on cyclins and cyclin-dependent kinases that regulate the progression of the cycle through the S and G2/M phases