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The impact of varying the timing of metformin administration on postprandial glucose metabolism is poorly defined

Participants receiving retatrutide 12 mg weekly achieved an average weight loss of 24.2% of body weight at 48 weeks the largest weight reduction recorded for any anti-obesity medication to date

Beyond weight loss and diabetes management, recent studies suggest GLP-1 drugs may offer other health benefits, too from treating addiction to lowering the risk of dementia

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Lancet 367 , 15131519 (2006)