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It simply means that the scientific review starts earliersomething that can be especially valuable for medicines targeting serious diseases with limited treatment options

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This was the case in 1999, when American Home Products, which was the maker of the diet drug fen-phen, created a $4.83 billion fund to settle lawsuits after users developed heart problems

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Ocular Very common (10% or more): Diabetic retinopathy (up to 20.1%) Common (1% to 10%): Retinal disorders, diabetic retinopathy complications Uncommon (0.1% to 1%): Nonproliferative retinopathy Very rare (less than 0.01%): Nonarteritic anterior ischemic optic neuropathy (NAION) Diabetic retinopathy complications included need for retinal photocoagulation, need for treatment with intravitreal agents, vitreous hemorrhage, and onset of diabetes-related blindness