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The most esteemed is the VinFuture Grand Prize, valued at US$3 million, making it one of the largest annual prizes globally

Published human exposure is limited to pharmacokinetic/pharmacodynamic study and a completed Phase II trial

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Ldlr -/- and Apoe -/- mice) after lethal irradiation to ablate host hematopoietic cells is commonly used to study the effect of specific genes expressed by macrophages and other hematopoietic cells on atherogenesis (99)