Jan 2020;9(1):151-159
10.1002/pbc.21037 21 LiD.WangH.QinC.DuD.WangY.DuQ.et al (2024)
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A similar phenomenon has been observed at the calcitonin receptor, another class B1 GPCR, where human calcitonin, with a fast off-rate, turns over G protein faster than salmon calcitonin, which has a slow off-rate, and this was related to differences in the residency time of the G protein on the receptor and to the sensitivity of the G protein to GTP 35