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Drug-induced malabsorption: Long-term medications like metformin or proton-pump inhibitors can reduce B12 absorption

602,780,781 Another crucial focus lies in F-1,6-BP, which is converted into F-6-P by FBP1, impacting the balance between glycolysis and gluconeogenesis and thereby regulating the equilibrium of these processes

In addition, ORI@CPD-Lipo nanoparticles significantly enhanced antitumor efficacy compared with the free ORI, non-targeted ORI@Lipo, and CKAAKN-blocked ORI@CPD-Lipo, which could be attributed to improved drug cellular uptake mediated by ORI@CPD-Lipo nanoparticles and the cytotoxic effects of the released ORI from the nanoparticles

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Initially, they had planned to continue the study for a further year, but because of the lack of positive results, they cancelled the extension

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