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Patients were followed for a median of 15.9 months, with 84.7 percent of patients assigned to oral semaglutide and 90.1 percent of patients assigned to placebo completing the trial

A shorter-term appetite suppressant that works through a different mechanism than GLP-1 medications reducing hunger through the central nervous system rather than hormonal pathways

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Those medications work through fewer receptor pathways and have lower maximum efficacy in clinical trials

Some women experience temporary nausea, flushing, or headache, but these effects are usually mild and short-lived

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