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For influenza virus, the ability of HA stem-targeting nAbs to induce ADCC but their rather weak neutralizing activity compared with nAbs to the HA head domain, which have weak interaction as immune complexes with FcRs but potent neutralizing activity, probably explains the dependence of anti-stem nAbs (but not anti-head nAbs) on Fc-dependent effector functions for protective efficacy 173

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Concentration = 50 mg 2 mL = 25 mg/mL Per unit (mg) = 25 100 = 0.25 mg per unit Per unit (mcg) = 0.25 mg 1000 = 250 mcg per unit Cross-check with the shortcut: (50 2) 10 = 25 10 = 250 mcg per unit Now a 100 mg vial and 5 mL: Concentration = 100 mg 5 mL = 20 mg/mL Per unit = (100 5) 10 = 20 10 = 200 mcg per unit If you want to check any figure in the tables below without doing it by hand, our reconstitution and dosage calculator runs the same arithmetic and will reproduce these numbers exactly

"I mean that the skin does not look healthy

Dec 2024;11(4):468-483