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Quick Answer: Millions of Americans currently use GLP-1 receptor agonists, with prescription rates showing substantial year-over-year growth as one of the fastest-expanding pharmaceutical classes in the United States

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For many people, food is a reliable source of small dopamine hits. Taking that away abruptly can blunt reward processing, leaving patients feeling emotionally flat

Changes in blood sugar patterns, eating behaviors, and energy levels all feed back into mood regulation, creating a complex interaction rather than a direct drug effect

The weight loss and improved insulin sensitivity it produces are well-established drivers of inflammation reduction