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In addition to its activity against hyperglycemia, DPP-4i has shown beneficial cardiovascular effects including cardioprotective action, endothelial protection, and an anti-hypertensive effect

R., Helmink, B

FASEB J (2003) 17(8):90810

Cayenne Pepper was included because Cayenne pepper (Capsicum frutescens) contains compounds like capsaicin and a unique antifungal saponin called CAY-1, which have shown activity against multiple fungal strains

This selectivity occurs because AOD-9604 does not bind to growth hormone receptors in muscle tissue and works primarily through beta-3 adrenergic receptors that are predominantly expressed in fat cells