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This condition is known as GH deficiency (GHD) but in analogy with other pituitary deficiencies leading to peripheral hormone deficiencies the term secondary IGF-I deficiency was proposed (Rosenfeld et al)

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PYY is usually stored in endocrine cells of intestinal mucosa as 36-amino-acid peptide (67), but in the blood circulation it is converted into truncated form, PYY3-36, acting via Y1, Y2, Y3 and Y5 receptors

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