During aging, glutathione levels appear to decline in a number of tissues, thereby putting cells at increased risk of succumbing to stress
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Elevated levels of oxidative stress markers have been consistently reported in ME/CFS, including malondialdehyde (MDA), isoprostanes, 8-OH-deoxyguanosine, 2,3 diphosphoglyceric acid, thiobutyric acid, and protein carbonyls
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doi: 10.1136/annrheumdis-2014-206106 43 SchaferPHKivitzAJMaJKorishSSutherlandDLiLet al
Shin, D