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Importantly, this does not depend on the body weight, which can lead to errors in estimation most oncology therapeutics are actually calculated based on surface area, said the authors, one of whom explained this further on Twitter

The results of the analysis should be interpreted in the context of the study scope, real-world setting and data source

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Notably, the efficacy of atorvastatin is poorly correlated with C max [44], probably due to complex pharmacokinetics of drug metabolites with longer half-life compared to the parent compound