A pilot study of 100 non-PCOS patients under 40 (50 myo-inositol, 50 control) by Lisi et al

Ingredients Purified water, butylene glycol, niacinamide (50,000 ppm), panthenol (50,000 ppm), tranexamic acid (40,000 ppm), 1,2-hexanediol, neopentyl glycol dicaprate, caprylic/ Capric triglyceride, sorbitol, lingonberry extract, Irish moss extract, shea butter, sugarcane extract, alpha-arbutin, bifida fermentation lysate, sodium hyaluronate, neem flower extract, holy basil leaf extract, Indian neem tree leaf extract, turmeric root extract, Chamsan homal extract, white wood ear mushroom extract, pentylene glycol, glycerin, 3-O-ethylascorbic acid (2,000 ppm), bisabolol, tromethamine, ethyl Hexylglycerin, adenosine, hydrogenated lecithin, allantoin, glutathione (100 ppm), ceramide NP, beta-glucan, dipotassium glycyrrhizate, tocopherol, ascorbic acid (1 ppb), ascorbyl glucoside (1 ppb) , tocopheryl acetate, hydroxypropylcyclodextrin, ubiquinone, thioctic acid, potassium hydroxide, behenyl alcohol, carbomer, xanthan gum, disodium EDTA Ingredients subject to change at manufacturer's discretion

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Metformin has been studied as a possible treatment for PCOS, and it has been suggested that it can help reduce weight in women who suffer from the condition
Cai H, Harrison DG
The accumulation of misfolded proteins leads to severe ER stress (ERS), which activates the unfolded protein response (UPR) (Oakes and Papa, 2015)