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doi: 10.1016/S1570-0232(02)00501-9

The Mechanism of First-Generation GLP-1s GLP-1 (glucagon-like peptide-1) is a hormone naturally released in the gut after eating

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While these potential benefits are appealing, the potential downsides do need to be considered:: Less Potent Effect The primary drawback of microdosing semaglutide is that it may not produce the same effectiveness as standard doses, especially when it comes to weight loss and blood sugar control