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NNMT pathway research, NAD metabolism models, metabolic signaling studies

Excessive NNMT in the body is associated with aging and age-related diseases, as well as disruptions to systems that regulate metabolism and weight

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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

The compound works within the body to help reactivate dormant metabolic processes and restore a more youthful rhythm of energy and fat regulation