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Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in FUSDelta14 knockin mice

This has immediate implications for the clinical management of cancer patients by alleviating the risk of ovarian failure from chemotherapy as a consideration in oncology, providing a potential alternative to cryopreservation protocols that require invasive superovulation and oocyte pick-up procedures, which can delay cancer treatment, and may have limited success rates (Bertoldo et al, 2020b

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immunotherapeutic approaches in asthma